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Focus on Healthy Aging - I have terrible heartburn. What can I do to relieve it?

admin — Mon, 12 Jan 2009 03:51:40 +0000

Heartburn occurs when harsh stomach acids back up and come into contact with the delicate lining of the esophagus. It can feel like a burning pain in your chest and throat. Everyone’s heartburn triggers are a bit different, but you’re more likely to get it after eating anything spicy, fatty, or greasy.

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Eating a big meal or eating quickly also can trigger it. To avoid getting heartburn, try eating smaller portions, eat more slowly, and finish dinner at least 2 to 3 hours before going to bed, because lying down can allow more acids to move up into the esophagus. There are several over-the-counter medications available to treat heartburn, including antacids (Tums, Maalox, Rolaids), which neutralize stomach acids, and histamine-2 or H2 blockers (Pepcid AC and Zantac 75), which block acid production in the stomach. A newer family of heartburn drugs called proton pump inhibitors (Prilosec) that are also available over the counter work by blocking stomach acid secretion. Because the symptoms of heartburn can mimic those of a heart attack, get immediate medical help if you have chest pain that lasts more than a few minutes, or any other symptoms associated with a heart attack (nausea, dizziness, shortness of breath). See your doctor if your heartburn doesn’t respond to treatment, or if you notice blood in your stools (tarry or black stools), chest pain, choking, difficulty swallowing, or unexplained weight loss.
COPYRIGHT 2006 Belvoir Media Group, LLC
COPYRIGHT 2008 Gale, Cengage Learning

Chain Drug Review - Antacid tablets

admin — Sat, 10 Jan 2009 08:41:04 +0000

Antacid tablets

% change % change
vs. vs.
Trade class Dollar sales year ago Unit sales year ago

TOTAL MASS MARKET $1,029,862,000 11.3% 144,909,100 2.4%
([dagger])
DRUG STORES $536,123,600 14.3% 65,071,350 5.8%
SUPERMARKETS $385,440,900 6.5% 64,064,370 -1.0%

Best-sellers in drug stores

Brand Manufacturer Dollar sales

Prilosec OTC Procter & Gamble $199,977,600
Pepcid AC Johnson & Johnson/Merck $38,135,840
Zantac 150 Johnson & Johnson $34,627,390
Pepcid Complete Johnson & Johnson/Merck $24,055,870
Gas X Novartis Consumer Health $22,402,180
Tums Ex GlaxoSmithKline $21,056,910
Zantac 75 Johnson & Johnson $18,037,200
Rolaids Johnson & Johnson $17,273,430
Tums Ultra GlaxoSmithKline $12,279,670
Lactaid Fast Acting McNeil Consumer Products $9,318,543

Dollar sales Dollar Dollar share
Brand % change share % change

Prilosec OTC 32.4% 37.3% 5.1%
Pepcid AC 1.2% 7.1% -0.9%
Zantac 150 47.4% 6.5% 1.4%
Pepcid Complete 8.4% 4.5% -0.2%
Gas X 9.6% 4.2% -0.2%
Tums Ex -7.7% 3.9% -0.9%
Zantac 75 -22.9% 3.4% -1.6%
Rolaids 8.9% 3.2% -0.2%
Tums Ultra 30.6% 2.3% 0.3%
Lactaid Fast Acting 75.1% 1.7% 0.6%

Unit sales Unit Unit share
Brand Unit sales % change share % change

Prilosec OTC 10,515,850 25.9% 16.2% 2.6%
Pepcid AC 3,809,285 -12.5% 5.9% -1.2%
Zantac 150 3,019,821 26.3% 4.6% 0.8%
Pepcid Complete 2,298,422 -4.2% 3.5% -0.4%
Gas X 3,818,775 11.3% 5.9% 0.3%
Tums Ex 6,310,972 -6.7% 9.7% -1.3%
Zantac 75 1,978,632 -22.4% 3.0% -1.1%
Rolaids 6,513,150 2.5% 10.0% -0.3%
Tums Ultra 2,490,434 31.6% 3.8% 0.8%
Lactaid Fast Acting 873,955 69.7% 1.3% 0.5%

* Private label brands account for 12.2% of dollar sales and 16.6% of
unit sales.

Drug Store News - Digesting an acquisition: Patrick Hennig, Boehringer Ingelheim

admin — Tue, 06 Jan 2009 05:28:05 +0000

Following the announcement that Johnson & Johnson would acquire Pfizer Consumer Healthcare, Boehringer Ingelheim Pharmaceuticals entered into an agreement with Johnson & Johnson and Pfizer to acquire the U.S. rights to the over-the-counter Zantac product line for $509.5 million in cash.
Drug Store News caught up with Boehringer Ingelheim’s Patrick Hennig for his thoughts on Boehringer’s digestive property.
DrSN: What does the Zantac acquisition mean for Boehringer Ingelheim?
Hennig: Zantac is a great strategic fit that complements our existing OTC franchise in the United States. We now have two powerful brands–Zantac and Dulcolax–that compete in the two largest segments of the GI category–acid reducers and laxatives

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DrSN: How would you characterize Zantac’s position in the marketplace?
Hennig: Zantac is a leading OTC brand competing successfully in a large and important retail category. Zantac has had strong consumption growth throughout 2005 and 2006 driven by the successful introduction of Zantac Maximum Strength, impactful advertising and promotional programs. We believe that Zantac has very positive consumer equity and a strong medical heritage.
DrSN: When will BI assume the marketing of Zantac?
Hennig: We assumed advertising and promotion responsibilities in January 2007 and hit the ground running. Right away, Zantac was being supported with national TV and radio advertising, couponing and value-added, special-pack programs.
DrSN: Does BI plan to keep the marketing expenditure on par with what Pfizer had historically committed to the brand, or will that marketing budget grow?
Hennig: Our vision for Zantac is to develop a strong and sustainable consumer brand. We are building upon and enhancing the programs that have been executed in the past…. Our focus right now is on a seamless transition for our retail partners and consumers. We are driving the business forward with a number of programs including national television and radio along with a variety of consumer promotion programs.
COPYRIGHT 2007 Reproduced with permission of the copyright holder. Further reproduction or distribution is prohibited without permission.
COPYRIGHT 2008 Gale, Cengage Learning

Business Wire - Taro Receives Tentative Approval for Ranitidine Syrup ANDA

admin — Sat, 03 Jan 2009 14:27:54 +0000

Generic Equivalent of Zantac[R] Syrup
HAWTHORNE, N.Y. — Taro Pharmaceutical Industries Ltd. (”Taro,” Pink Sheets: TAROF) reported today that it has received tentative approval from the U.S. Food and Drug Administration (”FDA”) for its Abbreviated New Drug Application for Ranitidine Syrup (Ranitidine Oral Solution USP), 15 mg/mL (”ranitidine syrup”).
Ranitidine syrup is a prescription product used for the treatment of ulcers, gastroesophageal reflux disease, or GERD, and other gastro-intestinal disorders. The FDA has determined that Taro’s ranitidine syrup is safe and effective for use when compared with the reference listed drug product, GlaxoSmithKline’s Zantac[R] Syrup, 15 mg/mL.

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The tentative ANDA approval for Taro’s ranitidine syrup is an FDA determination that Taro’s ANDA submission for this product currently satisfies the substantive requirements for approval, subject to the expiration of all relevant patents or statutorily imposed exclusivities and restrictions (currently expected to occur during May 2009), or any new information that may come to the FDA’s attention. Tentative approvals do not grant marketing rights; a company may only market a product upon receiving final approval for an ANDA submission.
According to industry sources, Zantac[R] Syrup has annual U.S. sales of approximately $125 million. It is expected that when Taro receives final FDA approval of its ANDA, there will be additional generic competition for Zantac[R] Syrup.
Taro Pharmaceutical Industries Ltd. is a multinational, science-based pharmaceutical company, dedicated to meeting the needs of its customers through the discovery, development, manufacturing and marketing of the highest quality healthcare products. For further information, please visit www.taro.com.
Certain statements in this release are forward-looking statements within the meaning of the Private Securities Litigation Reform Act of 1995, including statements regarding Taro’s ranitidine syrup product. Although Taro Pharmaceutical Industries Ltd. believes the expectations reflected in such forward-looking statements to be based on reasonable assumptions, it can give no assurance that its expectations will be attained. Factors that could cause actual results to differ include failure to receive final approval for Taro’s ANDA submission for ranitidine syrup; the granting of additional exclusivities or restrictions to Zantac[R] Syrup; industry and market conditions; slower than anticipated penetration of new markets; physician, pharmacist or patient acceptance of Taro’s ranitidine syrup; changes in the Company’s financial position; regulatory actions; and, other risks detailed from time to time in the Company’s SEC reports, including its Annual Reports on Form 20-F. Forward-looking statements speak only as of the date on which they are made. The Company undertakes no obligation to update, change or revise any forward-looking statements, whether as a result of new information, additional or subsequent developments or otherwise.
COPYRIGHT 2007 Business Wire
COPYRIGHT 2008 Gale, Cengage Learning

Philadelphia Inquirer, The - Glaxo will pay billions to IRS

admin — Mon, 29 Dec 2008 15:59:47 +0000

In the biggest tax settlement in U.S. history, the drug giant GlaxoSmithKline P.L.C. has agreed to pay $3.4 billion to the federal government in a case with tax implications for other multinational corporations. GlaxoSmithKline, based in London with a U.S. headquarters in Philadelphia, said it was settling to avoid a far bigger potential hit from allegations that it undervalued its U.S.

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profit on nine products - including the heartburn medicine Zantac and the asthma drug Advair - between 1989 and 2005. The large settlement was seen as a victory for the IRS in its long battle against “transfer pricing,” in which multinational firms ascribe revenue from intangible products like patents and development rights to subsidiaries in low-tax countries, and allocate expenses to high-tax countries, as a way of minimizing taxes. “The IRS won. Everybody knows this is going on” among global companies, said Jennifer Blouin, an accounting professor at the …

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Chain Drug Review - Boehringer to buy Zantac

admin — Fri, 26 Dec 2008 08:46:15 +0000

RIDGEFIELD, Conn. — Boehringer Ingelheim Pharmaceuticals Inc. is buying the Zantac brand from Johnson & Johnson for $505.5 million.
Sale of the nonprescription heartburn drug is contingent on J&J completing its planned acquisition of the consumer health business of Pfizer Inc.
“Zantac is an excellent strategic fit,” says J. Martin Carroll, president and chief executive officer of Boehringer Ingelheim, noting that it complements the company’s O-T-C line.
In June J&J and Pfizer announced that the former would pay $16.6 billion for Pfizer’s nonprescription drugs and consumer health products business.

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That deal is expected to close by the end of the year, and the Zantac transaction is intended to clear the Pfizer purchase, explains a J&J spokesman.
“Zantac is an excellent consumer brand with a strong market position and a bright future,” says Patrick Henning, vice president of sales and marketing for Boehringer Ingelheim’s consumer health care unit.
COPYRIGHT 2006 Racher Press, Inc.
COPYRIGHT 2008 Gale, Cengage Learning

MMR - Winn-Dixie

admin — Tue, 23 Dec 2008 16:12:39 +0000

The supermarket operator highlighted several offers on its online flyer for Dublin, Ga., good through February 6, including selected PepsiCo Inc. 24-packs of Pepsi or Aquafina water, two for $11 ; Procter & Gamble Co. Pampers diapers or jumbo training pants, selling for $7.99; and Glaxo-SmithKline PLC Zantac 75 or Zantac 150, 24- to 30-count, selling for $7.99.
n

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Internal Medicine News - New OTC Zantac dose

admin — Fri, 19 Dec 2008 09:03:46 +0000

Zantac is approved in a 150-mcg over-the-counter dose for the relief of heartburn associated with acid indigestion and sour stomach, and for the prevention of heart-burn associated with acid indigestion and sour stomach brought on by certain foods and beverages, when taken 30-60 minutes before eating or drinking. Contact Pfizer Inc., 800-223-0182 or 212-573-2323.

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Heartburn Reflux Remedy - How to Get Rid of Heart Burn Naturally

admin — Tue, 16 Dec 2008 05:21:39 +0000

Is there really a heartburn reflux remedy that works better than antacids? Yes, and it actually cures your acid reflux permanently by healing two things, your esophagus and lower esophageal sphincter.And how can you get rid of heart burn naturally? By using a variety of therapies that include your diet, some lifestyle habits, some herbs and some simple remedies which all work to regrow tissue on the esophagus and strengthen the sphincter.The Problem with AntacidsWe’ve all used them… antacids! The problem behind antacids is they can cause calcium-based kidney stones, constant diarrhea, low blood pressure, breathing problems and even osteomalacia (bones becoming very brittle). And if you do not believe me, next time you purchase a box of antacids, look on the warning label.The antacids, Zantac, Prilosec, Pipcid AC and Tagamet all have warnings that say, “Do NOT take for more than 14 days.” The problem occurs when most people ignore the warning because acid reflux symptoms continue to persist. In fact, millions of sufferers report more serious symptoms because of overuse of antacids.Is there a better option than antacids? Would you consider a heartburn reflux remedy?5 Ways to Get Rid of Heart Burn NaturallySocrates said, ‘Let food be your medicine, and medicine be your food.’ And this is the idea behind natural health. Because natural health centers on giving the body the tools to cure the problem.In the case of acid reflux, here are 5 ways to get rid of heartburn naturally by healing the esophagus and sphincter.1. An Apple- Though there is a little research behind this remedy, this remedy has worked wonders for thousands of our customers. In fact, this remedy is the reason why my dad cured his acid reflux naturally. We recommend carrying a slice of apple in a baggie just in case of a flare-up.2. Honey- If you love honey you are going to love this! Honey has been labeled a ‘miracle cure’ by many and has even been documented as a cure 3,000 years ago. A tablespoon of honey is all you need, twice a day. Honey has been reported to stimulate the regrowth of tissue which is just what the esophagus and sphincter need.3. Your Diet- There are things you should eat and there are foods you should avoid! Your esophagus and sphincter are damaged if you have consistent acid reflux. And foods can either heal or hinder your heartburn.Here are some quick rules of thumb: avoid spicy and acidic foods, limit coffee, cut back on smoking, and consume softer foods if possible.4. Water- You should make it a habit to drink a glass of water after every meal. This will keep the sphincter clean which creates a tight seal on the stomach. Therefore, the gases and stomach acids will stay in the stomach and not travel up to the esophagus.5. Apple Cider Vinegar- Yuck! But it works in most cases! By drinking an ounce of apple cider vinegar, you can actually increase the acids in your stomach. The acids will be able to digest your food more quickly and this will keep food and stomach acid where it should be… your stomach. Adding honey and acid cider vinegar is also a helpful taste tip!Curing Heartburn in 24 Hours or LessIf you are serious about saying ‘good bye’ to your acid reflux forever, take a moment and visit our Heartburn Reflux Remedy Website. With 22 years of natural health expertise, we offer a 100% guaranteed step by step natural remedy that has helped thousands.To cure your acid reflux in 24 hours or less, please visit us today!

Treatment for GERD - 8 Free Tips to Naturally Treat Acid Reflux and Heartburn

admin — Mon, 15 Dec 2008 00:16:36 +0000

You are not alone and you are not the only one searching for a treatment for GERD. Internet statistics show that people searching for GERD (gastro esophageal reflux disease), acid reflux and heartburn have been exponentially increasing over the past few years. And there are 2 possible reasons because of the high internet traffic on this subject.People are discovering that taking antacids will only treat the GERD for weeks! And millions of people have been permanently treating acid reflux with a simple treatment for GERD that is natural and heals the esophagus and lower esophageal sphincter (LES) and have been letting others know about! Some doctors are even recommending a few natural remedies.And as natural treatments are no longer taboo, many antacid companies are rethinking their products and some doctors are now using natural health remedies.Throw Away Your AntacidsHave you looked on the back of antacids such as Nexium, Tagamet, Omeprazole, Prvacid, and Zantac? You will notice that these antacids can only be used for an 8 week maximum. And there is a reason for this…The reason why you should stop taking antacids is because they cause your body to make a hormone called gastrin. Gastrin causes your stomach to make more stomach acid thus alleviating the heartburn problem. But gastrin also increases the risk of cancer to the digestive tract. Some say that antacids will someday be banned by the FDA?Thousands of our customers have thrown away there antacids permanently and you can too!8 Tips to Naturally Treat Acid Reflux with Your LifestyleResent research discusses how the body has an internal intelligence which allows itself to naturally heal if given the correct tools. Here are 5 tips to equip your body with the right tools to naturally treat GERD!1. If you smoke, stop.2. Do not drink alcohol.3. Lose weight to get to your ideal size.4. East smaller portioned meals.5. Wear loss fitting clothes to relieve pressure.6. Avoid lying down for 3 hours after a meal.7. Raise the head of your bed 6 to 8 inches by putting blocks under the bedposts- just using extra pillow will not help.8. Drink a tall glass of water after every meal.Using Natural Remedies Too!Take a second to learn what simple remedies you should be taking weekly to heal your esophagus and sphincter from the years of reflux damage.